Topic

How likely is it that it's MS?

SYMPTOMS *parasthesias in right leg (feels like hot stones from my butt to my toes just on the right side sometimes a little tingling but not a lot) *Bilateral leg weakness (both legs feel like they're giving out on me can't run or jog without feeling like my legs are disconnected from my body...also tripping a lot and going down stairs is difficult) *Right eye cloudy for the last 3-4 days *Strange sensation in my neck and head when I turn to look far to the right also when I press on my neck on the right side *dropping things occasionally without reason difficulty putting my thoughts into words at times mood swings and irritability *balance/coordination issues HISTORY of: ocular migraines normal headaches almost daily 2 years ago ocular migraine doubled with parasthesia of foot (very mild and went away-never investigated) vision changes requiring glasses 4 years ago for night vision and distances and 4 months ago a severe headache for 14 days (constant throbbing) MRI *T2/FLAIR hyperintensity lesion involving the subcortical white matter of the left paramedian frontal lobe and precentral gyrus (0.5x0.3x1.0 cm) *5 mm lesion left mid body of corpus callosum 2 mm lesion posterior left body of corpus callosum *A formal mid or lesion along the margin of right anterior body of corpus callosum IMPRESSION: Focal white matter lesion within the posteromedial left frontal lobe white matter involving the left precentral gyrus white matter as well as three lesions within and along the margins of the corpus callosum. The location and distribution is suggestive of demyelinating disease such as multiple sclerosis. Clinical and CSF correlation is suggested. There are no enhancing lesions to suggest active demyelination. CBC CMP TSH all WNL Setting neuro apt tomorrow worrying. Just want to know some percentages or likelihood of MS vs. differential based on MRI and symptoms.

2015-02-05 11:43:31

David

Replies

Contents

Hi! I can appreciate your worries regarding the results of MRI. As the MRI report suggests you will need further tests to confirm the diagnosis. This is because increased T2/Flair signals indicate small vessel ischemic disease or changes of brain blood vessels. Since there is no contrast enhancement you do not have a new or active demyelinating lesion. What is important is that multiple hyperintense lesions on T2/Flair could also occur in Alzheimer's or Wilson's Disease migraine headaches diabetes high blood pressure and high cholesterol. However generally a T1 hypointense or a T2 hyperintense lesion in corpus callosum is strongly suggestive of MS. So based on this aspect the chances of MS are high but nothing can be said for sure without a CSF study. Symptom wise yes your symptoms are suggestive of a neurological disorder like MS. However the symptoms can also be due to raised intracranial pressure benign intracranial hypertension or due to multiple nerve compression. For the confirmed diagnosis of MS you will need a spinal tap. During this tap the CSF pressure will be measured and this will indicate whether you have raised intracranial pressure or benign intracranial hypertension or not. Multiple nerve compression can be diagnosed through a spine MRI EMG and NCV tests. Please discuss all this with your neurologist. Good Luck and take care!

2015-02-05 11:43:58

Amy