I had a high risk exposure almost 10 weeks ago. I took one 40mg dose of Humira two to three weeks before exposure. 1.Will that one dose of Humira affect or prolong the production of Hiv antibodies or p24 antigen. 2. I've been having symptoms since week 2 and have gotten worse since. It started with a rash on my torso. some of the rashes looked like purple streaks and some looked like pink spots. they weren't that many and they didn't stay long. they would appear and go away in a couple of days. Since week 2 I've lost 12 pounds I had a sore throat I've had stomach pain mostly lower left. I've been having night sweats muscle pain and muscle weakness and muscle twitching. I feel tired a lot and I have tenderness under my armpits and around groin that comes and goes. Ive had some red spots on my arms and legs know my neck is starting to feel sore. I do have a cough but its not dry and I do smoke a lot. 3. I do have psoriasis psoriatic arthritis and gout. 4. Negative antibody test at week 4. Negative Rna Pcr quantative test at week 5. negative antibody at week 5. Negative AG/AB 4th generation at week 7. Negative rapid POC antibody at week 9. I don't know what to do. With all the symptoms ive been having wouldn't I have tested positive by know if I was infected? My body temps have been all over the place. No high fever but I did have a low grade fever 99.1 to 99.5 for a couple of days but it would come and go maybe last an hour and would go down if I went into a different room. What do you suggest? Any specific test? ive also noticed a swollen lymph node on the side of me neck and a very tiny one one the back of my neck. Ive been taking Klonopin for 2 months because of the stress and anxiety.
2015-04-07 10:44:00
Welcome to the Forum. I'll be pleased to comment. Before I get to your specific questions let me remind you that even most high risk persons do not have HIV or other STIs and when they do most exposures do not lead to infections. With this let's get to your specific questions: 1.Will that one dose of Humira affect or prolong the production of Hiv antibodies or p24 antigen. No the Humira is an immune modulator which sometimes permits existing infections that many people have to re-occur (relapse) and makes recipients more susceptible to certain infections caused by fungus or to tuberculosis-type bacteria. Theoretically Humira might delay development of antibodies to HIV but there is no data to suggest that it makes persons more susceptible to HIV and there is no theoretical reason that Humira would make p24 antigen harder to detect. 2. Your rash sounds nothing like the rash of HIV. Your other symptoms are non-specific. 3. Your psoriasis psoriatic arthritis and gout do not make you more vulnerable to HIV. 4. If your symptoms were due to HIV your PCR test would have been positive. The negative test is strong evidence that you did not get HIV form your high risk exposure. My advice is to not worry further about HIV form your exposure over two months ago. There is strong evidence that you are not infected. There may be something else going on and I would suggest that you talk with your doctor for evaluation of what might be going on but I would not be worried about HIV.
2015-04-07 10:44:32
